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Friedrich Scheiflinger Selected Research

ADAMTS13 Protein

6/2012A new mouse model mimicking thrombotic thrombocytopenic purpura: correction of symptoms by recombinant human ADAMTS13.
10/2009von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke.
10/2006In-vitro and in-vivo consequences of mutations in the von Willebrand factor cleaving protease ADAMTS13 in thrombotic thrombocytopenic purpura.
8/2005Rituximab prevents recurrence of thrombotic thrombocytopenic purpura: a case report.
5/2005Complement factor H mutation in familial thrombotic thrombocytopenic purpura with ADAMTS13 deficiency and renal involvement.
6/2004Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura.
11/2003Nonneutralizing IgM and IgG antibodies to von Willebrand factor-cleaving protease (ADAMTS-13) in a patient with thrombotic thrombocytopenic purpura.
3/2003ADAMTS13 gene defects in two brothers with constitutional thrombotic thrombocytopenic purpura and normalization of von Willebrand factor-cleaving protease activity by recombinant human ADAMTS13.

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Friedrich Scheiflinger Research Topics

Disease

18Thrombotic Thrombocytopenic Purpura
01/2022 - 11/2002
14Hemophilia A (Haemophilia)
12/2020 - 11/2003
9Hemorrhage
01/2022 - 03/2006
7acquired Thrombotic thrombocytopenic purpura
11/2015 - 11/2003
5Hemophilia B (Haemophilia B)
11/2021 - 11/2013
5Thrombosis (Thrombus)
01/2017 - 03/2006
5Thrombotic Microangiopathies
06/2012 - 08/2005
4Inflammation (Inflammations)
01/2018 - 03/2006
4Neoplasms (Cancer)
01/2018 - 04/2007
2Glomerulonephritis
02/2018 - 09/2015
2Thrombocytopenia (Thrombopenia)
11/2015 - 08/2005
2Sepsis (Septicemia)
03/2012 - 04/2007
2Systemic Lupus Erythematosus (Libman-Sacks Disease)
05/2010 - 08/2005
1Sickle Cell Anemia (Hemoglobin S Disease)
01/2022
1Nephritis
02/2018
1Vesicular Stomatitis
11/2017
1Ischemic Stroke
12/2016
1Ovarian Neoplasms (Ovarian Cancer)
11/2016
1Hemolytic Anemia
11/2015
1Enterocolitis
09/2015
1Prostatic Neoplasms (Prostate Cancer)
07/2013
1Myocardial Ischemia (Ischemic Heart Diseases)
12/2012
1Myocardial Infarction
12/2012
1Body Weight (Weight, Body)
06/2012
1Contact Dermatitis (Eczema, Contact)
03/2012
1Immunoglobulin G4-Related Disease
08/2011
1Purpura
05/2010
1Brain Injuries (Brain Injury)
10/2009
1Stroke (Strokes)
10/2009
1Synovitis
06/2006
1Hemorrhagic Shock
03/2006
1Wounds and Injuries (Trauma)
03/2006
1Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome)
08/2005
1Neurologic Manifestations (Neurological Manifestations)
05/2005
1Chronic Kidney Failure (Chronic Renal Failure)
05/2005

Drug/Important Bio-Agent (IBA)

17thiamine triphosphorate (TTP)IBA
01/2022 - 11/2002
11AntibodiesIBA
01/2018 - 11/2003
10von Willebrand FactorIBA
01/2017 - 11/2002
8ADAMTS13 ProteinIBA
06/2012 - 03/2003
7AutoantibodiesIBA
04/2014 - 11/2003
6Proteins (Proteins, Gene)FDA Link
12/2020 - 03/2003
6Immunoglobulin G (IgG)IBA
01/2016 - 11/2003
5Metalloproteases (Metalloproteinases)IBA
01/2022 - 08/2005
5Factor IX (Coagulation Factor IX)FDA LinkGeneric
11/2021 - 11/2013
5Factor VIII (Coagulation Factor VIII)IBA
12/2020 - 06/2011
4ThrombospondinsIBA
01/2022 - 08/2005
4DisintegrinsIBA
01/2022 - 08/2005
4Protein Isoforms (Isoforms)IBA
02/2018 - 09/2015
4Macrophage Migration-Inhibitory FactorsIBA
02/2018 - 07/2013
3EpitopesIBA
04/2014 - 06/2004
3Neutralizing AntibodiesIBA
11/2013 - 05/2010
3Peptide Hydrolases (Proteases)FDA Link
12/2012 - 01/2004
2BAX 335IBA
11/2021 - 09/2018
2ThrombinFDA Link
01/2020 - 06/2015
2CytokinesIBA
01/2018 - 11/2016
2Complement System Proteins (Complement)IBA
11/2017 - 05/2005
2Pharmaceutical PreparationsIBA
11/2016 - 11/2013
2Immunoglobulin M (IgM)IBA
01/2016 - 11/2003
2lipoprotein-associated coagulation inhibitor (TFPI)IBA
06/2015 - 01/2014
2Immunoglobulins (Immunoglobulin)IBA
02/2015 - 01/2005
2Immunoglobulin IsotypesIBA
02/2015 - 04/2007
2Antigen-Antibody Complex (Immune Complex)IBA
04/2014 - 01/2012
2Amino AcidsFDA Link
03/2012 - 03/2003
2Rituximab (Mabthera)FDA Link
09/2005 - 08/2005
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2022
1Enoxaparin (Lovenox)FDA LinkGeneric
01/2022
17,7'- dimethoxy- (4,4'- bi- 1,3- benzodioxole)- 5,5'- dicarboxylic acid dimethyl ester (BDD)IBA
12/2020
1Factor XIa (Coagulation Factor XIa)IBA
01/2020
1Thromboplastin (Tissue Factor)IBA
01/2020
1Glycoproteins (Glycoprotein)IBA
11/2017
1LigandsIBA
01/2017
1Blood Proteins (Serum Proteins)IBA
01/2017
1Fibrinolytic Agents (Antithrombotic Agents)IBA
12/2016
1Tissue Plasminogen Activator (Alteplase)FDA Link
12/2016
1Mitoxantrone (Novantrone)FDA LinkGeneric
11/2016
1Doxorubicin (Adriamycin)FDA LinkGeneric
11/2016
1Cisplatin (Platino)FDA LinkGeneric
11/2016
1GlucocorticoidsIBA
09/2015
1Factor IXa (Coagulation Factor IXa)IBA
03/2015
1gamma-AIBA
03/2015
1fucoidanIBA
01/2015
1Biological ProductsIBA
01/2015
1Factor VIIa (Activated Factor VII)IBA
11/2013
1ferric chlorideIBA
03/2009
1Monoclonal AntibodiesIBA
06/2006
1Indicators and Reagents (Reagents)IBA
06/2006
1IronIBA
06/2006
1Histamine (Histamine Dihydrochloride)FDA Link
03/2006
1Ringer's SolutionIBA
03/2006
1Starch (Cornstarch)IBA
03/2006
1Hydroxyl RadicalIBA
03/2006
1Saline SolutionIBA
03/2006
1AntigensIBA
02/2006
1ImmunosorbentsIBA
08/2005
1EnzymesIBA
08/2005

Therapy/Procedure

9Therapeutics
11/2021 - 02/2013
1Plasma Exchange
10/2015
1Cardiopulmonary Bypass (Heart-Lung Bypass)
06/2015
1Transplantation
04/2007
1Resuscitation
03/2006